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Title: Endocrine disruption horizon scanning: priority and new endocrine disrupting chemicals
Author: S.D. Roast
Author: Agency: Bristol Environmental
Document Type: Monograph
Annotation: Environment Agency Project ID:EAPRJOUT_1123, Representation ID: 358, Object ID: 2387
This document reports on the priority endocrine disrupting chemicals (EDCs) identified by the main international regulatory organisations (including the European Commission (EC), the United States Environmental Protection Agency (US EPA), and Japanese ministries). A recently published compilation of all known lists of EDCs reported a total of 966 chemical compounds reported as having some degree of ED activity. More than half (539) are general chemical substances of anthropogenic origin, and a quarter (225) are biocides; pharmaceuticals contribute 58 substances, while 62 are naturally occurring chemical substances. The report also outlines the chemical substances used in experimental studies since 2000 (via the citation of EDCs in published journals). Studies of ED have used 156 different chemicals since 2000. However, the most frequently used chemicals (nonyl phenol, bisphenol A, tributyl tin, oestrone and ethinyloestradiol) are well-known EDCs; this probably reflects the number of studies investigating ED mechanisms as opposed to new EDCs. None of the chemicals treated as priorities on any of the published lists are new (all have been known to elicit ED effects for several years), but this may reflect the amount of evidence required for such chemicals to be on the priority lists. However, no new chemicals have been identified in the literature, or in consultation with experts in the field of ED from international regulatory organisations. From a UK perspective, the EC list is probably the most important for prioritisation purposes of ED and EDCs.
Publisher: Environment Agency
Subject Keywords: Endocrinological functionsRiversEstuariesCoastal watersInvertebratesResearchEnvironmental monitoringChemical compoundsPesticidesDrugsBrackishwater environmentFreshwater ecologyMarine environment
Extent: 70
Total file downloads: 304

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